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The only approved treatment to temporarily improve the appearance of frown lines between the brows and crow’s feet lines in adults.
BOTOX Cosmetic by Marshall

What to expect with BOTOX®

BOTOX® Cosmetic targets one of the underlying causes of frown lines and crow’s feet—the repeated muscle contractions from frowning and squinting over the years. Your specialist will inject these muscles with BOTOX® Cosmetic to temporarily reduce muscle activity. You will begin to notice a visible smoothing of your crow’s feet lines and frown lines between your brows.

For the crow’s feet area, your specialist will inject 3 areas of the orbicularis oculi, the muscle that frames the side of the eye. This will be repeated on the orbicularis oculi muscle on the other eye.

Injecting BOTOX® Cosmetic into the muscles that cause crow’s feet lines temporarily reduces the activity of those muscles. The result is a reduction in the appearance of those lines.

For the frown lines area, your specialist will administer 5 injections into muscles in your forehead—1 in the procerus muscle and 4 in the corrugator muscles.

Injecting BOTOX® Cosmetic into the muscles that cause frown lines temporarily reduces the activity of those muscles. The result is a reduction in the appearance of those lines.

BOTOX Muscle Diagram

How Does BOTOX® Cosmetic Work?


BOTOX Treatment Areas

Wrinkles result from a combination of many factors. It’s not just about cellular changes that can occur over time, reduction of collagen, or damage caused by free radicals in the sun and the environment. When you frown or concentrate, the muscles between your brows contract, causing your skin to furrow and fold. And when you squint, the muscles around your eyes contract and cause crow’s feet.

BOTOX® Cosmetic works beneath the skin’s surface and targets the underlying muscle activity that causes frown lines and crow’s feet.

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*Actual patient. Results may vary. Photos taken at maximum frown and/or full smile before and after treatment with BOTOX® Cosmetic at day 7. In two clinical studies for moderate to severe crow’s feet, 26.1% and 20.3% of people had ≥ 2-grade improvement at day 30. In one of these studies, 67.9% of people had mild or no crow’s feet at day 30 after treatment. In clinical studies for moderate to severe frown lines, physicians assessed 80% of people had significant improvement at day 30.

Frequently Asked Questions

BOTOX® Cosmetic is the only approved treatment to temporarily improve the appearance of both moderate to severe frown lines between the brows and crow’s feet lines in adults.

BOTOX® Cosmetic is one of the most extensively studied medical aesthetic treatments and is approved for cosmetic use in 78 countries.* BOTOX® Cosmetic has a record of experience that aesthetic specialists know and trust. And, the safety and efficacy of BOTOX® Cosmetic have been evaluated in both Allergan sponsored clinical trials as well as in 417 peer-reviewed articles in scientific and medical journals.

BOTOX® Cosmetic contains tiny amounts of a highly purified botulinum toxin protein refined from the bacterium, Clostridium botulinum. Formulations, potency, and approved doses vary among botulinum toxin products, which means that one product cannot take the place of another. Those are a few reasons why there is no such thing as a “generic” form of BOTOX® Cosmetic. There have been no studies to support that other products are Unit-to-Unit equivalent to BOTOX® Cosmetic.

BOTOX® Cosmetic targets one of the underlying causes of frown lines and crow’s feet—the repeated muscle contractions from frowning and squinting over the years. Your specialist will inject these muscles with BOTOX® Cosmetic to temporarily reduce muscle activity. You will begin to notice a visible smoothing of your crow’s feet lines and frown lines between your brows.
BOTOX® Cosmetic is a technique-sensitive treatment. You should not lose the ability to show expression when you are treated by someone who is licensed, trained, and a medical expert in facial anatomy. It is important to talk to our specialist about the results you want from treatment.
Some patients report that being injected with BOTOX® Cosmetic feels like a pinch. If you are concerned about discomfort, our specialist may apply a topical numbing cream before administering your treatment.
Three percent of patients experienced eyelid drooping in the frown lines studies and 1% of patients experienced eyelid swelling in the crow’s feet studies. Other possible side effects include: dry mouth; discomfort or pain at the injection site; tiredness; headache; neck pain; eye problems: double vision, blurred vision, decreased eyesight and dry eyes; and allergic reactions. These are not all of the possible serious side effects of BOTOX® Cosmetic. Please see the Important Safety Information including Boxed Warning and Medication Guide, and talk to your specialist.
Our specialist will discuss your treatment goals and perform a facial analysis to determine the appropriate treatments for you. The actual injection process takes about 10 minutes.
You may begin to notice results within 24 to 48 hours for moderate to severe frown lines, with results lasting up to 4 months.
For the crow’s feet area, our specialist will inject 3 areas of the orbicularis oculi, the muscle that frames the side of the eye. This will be repeated on the orbicularis oculi muscle on the other eye.

For the frown lines area, our specialist will administer 5 injections into muscles in your forehead—1 in the procerus muscle and 4 in the corrugator muscles.

After your treatment, you can resume your day. There is minimal downtime and your specialist may give you specific aftercare instructions.
Yes. BOTOX® Cosmetic has also been clinically evaluated in male patients. In clinical studies for moderate to severe frown lines, 17.5% of patients treated with BOTOX® Cosmetic were men. In the clinical studies for moderate to severe crow’s feet, male patients comprised approximately 10% of patients treated with BOTOX® Cosmetic.

According to the American Society for Aesthetic Plastic Surgery, 10% of all cosmetic procedures performed in the United States in 2014 were on men—that is more than 1 million cosmetic procedures. The number of cosmetic procedures for men increased by 273% from 1997 to 2014.

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